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Information developed by A. Please discuss with your doctor any questions or concerns you may have. Medical Tests. Definition Lactate dehydrogenase LDH is a protein that helps produce energy in the body. How to Prepare for the Test No specific preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain.
However, these elevations do not correlate well with proteinuria or other parameters of renal disease. On occasion a raised LD level may be the only evidence to suggest the presence of a hidden pulmonary embolus. Red blood cells contain much more lactate dehydrogenase LD than serum.
A hemolyzed specimen is not acceptable. LD activity is 1 of the most sensitive indicators of in vitro hemolysis. Causes can include transportation via pneumatic tube, vigorous mixing, or traumatic venipuncture. While increases in serum LD also are seen following a myocardial infarction, the test has been replaced by the determination of troponin. Tietz Textbook of Clinical Chemistry. This is a blood test that measures the level of lactate dehydrogenase LDH in your body.
LDH is an enzyme, or catalyst, found in many different tissues in your body. These include your red blood cells, skeletal muscles, kidneys, brain, and lungs. When your LDH rises, it means that tissues may have been damaged or are diseased. You may need this test if your healthcare provider believes you may have tissue damage or a disease. It may also be done if your provider thinks you've had a heart attack. If you've already been diagnosed with a specific disease, you may have this test so your provider can watch your condition and see if your treatment is working.
You may also have a lactate dehydrogenase isoenzyme test. Isoenzymes are like subunits or fractions that make up the total. The concentration of each isoenzyme is measured and depends on the tissue. LDH-5 is found mostly in the liver.
A higher than normal total LDH means possible tissue damage. Your healthcare provider might order a lactate dehydrogenase isoenzyme test to help find out which tissue is damaged or diseased. Test results may vary depending on your age, gender, health history, the method used for the test, and other things.
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